PoE 2: Guide to all Permanent Buffs from the Campaign

Overview

Path of Exile 2’s campaign offers a variety of quests and optional bosses that grant your character permanent buffs. However, some of these buffs are easy to overlook as they aren’t always highlighted during gameplay.

This guide provides a detailed breakdown of all the permanent buffs you can obtain by completing the Campaign on both Normal and Cruel difficulties.

 

List of Permanent Buffs

By the end of the Campaign, you can acquire the following permanent buffs:

• +20% to All Resistances (Don’t miss the Lightning Resistance buff, as it’s often overlooked)
• +24 Weapon Set Skill Points
• +100 Spirit
• +20 Maximum Life
• +8% Increased Maximum Life
• Choose One (Can be changed later, available twice):
  • +30% Increased Charm Charges
  • +15% Increased Mana Recovery from Flasks
• Choose One (Permanent choice):
  • +25% Increased Stun Threshold
  • +30% Increased Elemental Ailment Threshold
  • +25% Increased Mana Regeneration Rate
• Choose One (Permanent choice):
  • +10% Chaos Resistance
  • +5 to All Attributes
  • +15% Reduced Slowing Potency of Debuffs

Each buff source and the method to unlock it are detailed below. Unless stated otherwise, buffs are granted twice—once in Normal difficulty and again in Cruel. Note that the buffs granted during Cruel may differ slightly.

 

Permanent Buff Map Icons

To help players track their progress, the World Map features icons that indicate content tied to permanent buffs. These icons appear on the bottom left or right of the map symbols, and once the task is completed, the icon will be grayed out.

While every World Map is procedurally generated and unique to each player, the icons remain consistent:

• Skull Icons: Indicate Campaign or optional bosses
• Large Skull Icons: Mark Act bosses
• Chest Icons: Represent guaranteed loot
• Miscellaneous Icons: Denote side quests

 

Act 1 & Act 4

• Clearfell – Beira of The Rotten Pack

  • Buff: +10% Cold Resistance
  • Requirement: Kill the optional boss

• Hunting Grounds – Crowbell

  • Buff: +2 Weapon Set Passive Skill Points
  • Requirement: Kill the optional boss

• Freythorn – The King in the Mists

  • Buff: +30 Spirit
  • Requirement: Complete Rituals to summon the boss, then defeat it

• Ogham Farmlands – Una’s Hut

  • Buff: +2 Weapon Set Passive Skill Points
  • Requirement: Deliver Una’s Lute to Una

• Ogham Manor – Candlemass, The Living Right

  • Buff (Normal): +20 Maximum Life
  • Buff (Cruel): +8% Increased Maximum Life
  • Requirement: Kill the optional boss

 

Act 2 & Act 5

• Keth – Kabala, Constrictor Queen

  • Buff: +2 Weapon Set Passive Skill Points
  • Requirement: Kill the optional boss

• Valley of the Titans

  • Buff: Choose One (Choice can be changed by revisiting the location):
    • +30% Increased Charm Charges
    • +15% Increased Mana Recovery from Flasks
  • Requirement: Insert two relics (Kabala Clan Relic and Sun Clan Relic, found in Keth and The Bone Pits, respectively)

• Deshar – Final Letter

  • Buff: +2 Weapon Set Passive Skill Points
  • Requirement: Deliver the letter to Shambrin

• The Spires of Deshar – Sisters of Garukhan Shrine

  • Buff: +10% Lightning Resistance
  • Requirement: Explore the map and interact with the shrine

 

Act 3 & Act 6

• Jungle Ruins – Mighty Silverfist

  • Buff: +2 Weapon Set Passive Skill Points
  • Requirement: Kill the optional boss

• The Azak Bog – Ignagduk, The Bog Witch

  • Buff (Normal): +30 Spirit
  • Buff (Cruel): +40 Spirit
  • Requirement: Kill the optional boss

• The Venom Crypts – Venom Draught

  • Buff (Normal): Choose One (Permanent choice):
    • +25% Increased Stun Threshold
    • +30% Increased Elemental Ailment Threshold
    • +25% Increased Mana Regeneration Rate
  • Buff (Cruel): Choose One (Permanent choice):
    • +10% Chaos Resistance
    • +5 to All Attributes
    • +15% Reduced Slowing Potency of Debuffs
  • Requirement: Deliver the Venom Vial to Servi

• Jiquani’s Machinarium – Blackjaw, the Remnant

  • Buff: +10% Fire Resistance
  • Requirement: Use a Small Soul Core to open the boss’s room and defeat Blackjaw

• Aggorat – Blood Sacrifice

  • Buff: +2 Weapon Set Passive Skill Points
  • Requirement: Find the Sacrificial Heart from a monster drop and use it at the altar

 

This guide should help you track and maximize the buffs your character can receive throughout the campaign. Stay alert for optional bosses and quests, as many of these rewards are pivotal to strengthening your character for the challenges ahead!