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The world of Once Human is brimming with powerful tools of destruction, and this Once Human weapon tier list is your ultimate guide to navigating them. Weapons here aren’t just survival tools—they’re artifacts of a world gone wild, transformed by Stardust tech and alien elements. Some are reconstructed from old-world junk, while others are high-powered beasts built from mysterious materials. With PvE forming the majority of your gameplay experience, knowing which weapons dominate the current meta is essential. That’s where this guide steps in.
Weapons can be obtained through various means such as crafting, scavenging, or defeating enemies. Exploration plays a huge role—expect to uncover deadly gear in derelict zones or from high-value targets. You’ll also find blueprints and crafting materials to help create or enhance your arsenal. With so many paths to gear up, mastering your loadout is key to thriving in Once Human.
Our Once Human weapon tier list is informed by practical in-game performance across key areas like damage output, mod synergy, range effectiveness, and ease of use. Given the hybrid nature of survival and shooter gameplay, the best weapons are those that adapt well to varied challenges. Keep in mind, the meta is not static—balancing patches and new content often shake things up. Be sure to revisit this tier list regularly to stay on top of the game’s evolution.
Tier rankings are explained below:
Remember, while this Once Human weapon tier list is a valuable tool, your own playstyle and skill matter greatly. Even the best gun is only as good as the hands that wield it. Likewise, underrated weapons can turn into reliable options if used effectively.
Since PvE constitutes over 90% of your time in-game, this tier list was developed with PvE performance as the primary metric. Based on the most recent balance changes and Season 1 weapon meta, here’s where each gun stands.
| Tier | Weapons |
|---|---|
| S | AWS.338 Bullseye, SOCR - The Last Valor, MPS7 - Outer Space, DE.50 - Wildfire, DE.50 - Jaws |
| A | SOCR - Outsider, MG4 - Predator, DBSG - Doombringer, ACS12 - Corrosion, AWS.338 - Black Panther, DB12 - Raining Cash, Dual Fury |
| B | HAMR - Brahminy, Recurve Crossbow, S870 - Sandstorm, KVD - Boom! Boom!, DB12 - Backfire, MG4 - Mr. Squid, SN700 - Gulped Lore, MPS5 - Kumawink, KV-SBR - Little Jaws, KAM - Crank, R500 - Memento, KAM - Abyss Glance |
| C | R500 - Hammerhead Shark, G17 - Dusty, MPS7 - Div-Evo, Compound Bow, R500 - Hunter, MG4 - Wrath of Hades, ACS12 - Netherworld, HAMR - Crumble |

Weapons in this category offer the best all-around performance with amazing stats, lethal precision, and excellent adaptability. Perfect for any kind of encounter.
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A-tier weapons are reliable and strong, with just a few drawbacks that prevent them from reaching S-tier dominance. They shine when paired with strategic gameplay or specialized builds.
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These weapons can still serve well with the right handling and strategy, but they’re generally more limited. Expect trade-offs in handling, damage, or versatility.
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These weapons are rarely the best choice but might still have niche use cases. They’re mostly early-game filler or backup options when better gear isn’t available.
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Currently, the SOCR - The Last Valor takes the crown as the top-tier gun in Once Human. What makes it such a powerhouse? Its shrapnel bullet effect cuts through enemies with ease, delivering high burst and sustained damage across all encounter types. It’s flexible, deadly, and fits into nearly any build seamlessly.
Whether you’re playing solo or grouped up, this assault rifle stands out thanks to its consistent performance and high crit potential. It’s the meta weapon for PvE, and a fan-favorite for those diving into endgame content.
To acquire The Last Valor, players need to access the Wish Machine system and pursue its blueprint via two primary methods:
Though you can occasionally loot this weapon from world bosses or crates, these versions can’t be repaired and are generally unreliable for long-term use.
Starchrom is the currency you’ll need to unlock meta weapons like The Last Valor. Here’s how to farm it efficiently:
With these strategies, you’ll quickly stack up enough Starchrom to chase the strongest gear in the game.
The SOCR - The Last Valor stands as the top weapon in Once Human due to its unmatched versatility and impact in various combat situations. With the right setup, it becomes a dominant force across PvE encounters.
The MPS7 - Div-Evo excels at eliminating enemies quickly thanks to its rapid-fire capability and shrapnel effect, making it highly effective in close and mid-range battles.
Top-tier weapons in Once Human include the SOCR - The Last Valor, MG4 - Predator, and DBSG - Doombringer. These options provide a strong balance between firepower, control, and versatility for any combat scenario.
The R500 - Hammerhead Shark is praised for its accuracy, allowing players to deliver precise long-range shots, making it ideal for targeting high-priority enemies.
With its high critical hit potential, the SOCR - The Last Valor offers some of the highest damage in the game, especially when optimized through proper loadouts.
There’s no shortage of deadly gear in Once Human, but if you want to stay ahead of the curve, this Once Human weapon tier list is your go-to resource. The meta is clear—at least five weapons are top-tier right now, including The Last Valor, which stands at the pinnacle of power and flexibility.
Still, don’t ignore A and B-tier guns entirely. Many of them offer excellent value with the right build or strategy. The goal is to build toward meta gear while experimenting with what suits your style. Once you get The Last Valor, you’re well-equipped for any content Once Human throws at you.
Need help gearing up fast? Check out Gamer Choice—your trusted platform for Once Human accounts, items, and more.