Cassiopeia Mid Build

Cassiopeia Champion Guide

Role: Mage

Lane: Midlane

Cassiopeia Mid performs best with a build featuring Rod of Ages, Archangel's Staff, Rylai's Crystal Scepter, Liandry's Torment, and Zhonya's Hourglass. The most effective rune setup for Cassiopeia Mid includes Conqueror, Presence of Mind, Legend: Haste, and Last Stand in the primary tree, paired with Manaflow Band and Transcendence in the secondary tree.

Cassiopeia Champion Abilities

Serpentine Grace

Cassiopeia gains 4-72 bonus movement speed. Cassiopeia cannot purchase Boots items. Cassiopeia also gains an additional 1-18 bonus movement speed if her team obtains the Blessing of Noxus, for a maximum of 5-90 bonus movement speed (depending on level). P

Noxious Blast

Cassiopeia blasts noxious gas, poisoning enemies and dealing 10.71 / 15.71 / 20.71 / 25.71 / 30.71 (+10% of ability power) magic damage over 3 seconds for a total of 75 / 110 / 145 / 180 / 215 (+65% of ability power). Hitting a champion grants Cassiopeia 30 / 35 / 40 / 45 / 50% decaying over 3 seconds. Q

Miasma

Cassiopeia spews venom, leaving toxic clouds for 5 seconds. Enemies in the clouds take 20 / 25 / 30 / 35 / 40 (+10% of ability power) magic damage per second, are poisoned, grounded, and slowed by 40 / 50 / 60 / 70 / 80% for the same duration. W

Twin Fang

Cassiopeia launches deadly fangs, dealing 52-120 (+10% of ability power) magic damage (depending on level). If the enemy is poisoned, they take an additional 20 / 40 / 60 / 80 / 100 (+55% of ability power) magic damage and Cassiopeia restores 10 / 11.5 / 13 / 14.5 / 16% ability power as health.

If this kills the target, this ability's cooldown is refunded. E

Petrifying Gaze

Cassiopeia unleashes a petrifying gaze, dealing 150 / 250 / 350 (+50% of ability power) magic damage and stunning enemies facing her for 2 seconds. Enemies facing away are slowed by 40% decaying over the same duration instead. R

Cassiopeia Summoner Spells

Flash

Flash is a location-targeted summoner spell that causes your champion to blink to the location in range of your cursor.

Teleport

Teleport is a unit-targeted summoner spell that blinks your champion to the target allied unit after a few seconds of channeling.

Teleport transforms into Unleashed Teleport after 10:00.

Cassiopeia Runes

Cassiopeia Items

Cassiopeia Ability Order

Cassiopeia Matchups Overview

Strong against

Kayle

Zed

Ekko

Sylas

Ryze

Azir

Weak against

Anivia

Akshan

Karma

Vel'Koz

Zoe

Annie

Cassiopeia Tips and Tricks

In the early game, always keep an eye on your mana pool when trading as it depletes quickly, especially when engaging with the enemy. Only commit to trades when you’ve successfully landed your Q, as this allows you to follow up with multiple E's for a favorable trade. Cassiopeia has strong all-in potential at level 2, especially when using her Q and E combination. If you're in a favorable matchup against a squishy champion, aim to secure an early lead once you reach this level.

Cassiopeia Best Build, Runes, Items

Most Popular

The best Cassiopeia Mid build includes Flash and Teleport as Summoner Spells. For runes, pick Conqueror as the keystone, followed by Presence of Mind, Legend: Haste, and Last Stand in the primary tree, and Manaflow Band with Transcendence in the secondary tree. Rune shards should be Adaptive Force for offense, Adaptive Force for flex, and Health Scaling for defense. For items, build Rod of Ages as your first item, followed by Archangel's Staff. Finish the build with Rylai's Crystal Scepter, Liandry's Torment, and Zhonya's Hourglass. For skill order, max E first, followed by Q and W.

Alternative

An alternative build for Cassiopeia Mid uses Flash and Teleport as Summoner Spells, with Conqueror as your keystone. Follow this with Presence of Mind, Legend: Haste, and Last Stand in the primary tree, and Manaflow Band with Transcendence in the secondary tree. For rune shards, use Adaptive Force, Adaptive Force, and Health Scaling. The items for this build include Rylai's Crystal Scepter as the first item, followed by Archangel's Staff. Then finish with Liandry's Torment, Zhonya's Hourglass, and Void Staff. For ability max order, prioritize E, then Q, followed by W.

Off-Meta

If you're looking to try an off-meta Cassiopeia Mid build, use Flash and Teleport as your Summoner Spells. Pick Phase Rush as your keystone, with Manaflow Band, Transcendence, and Scorch in the primary tree, and Coup de Grace with Presence of Mind in the secondary tree. Use Adaptive Force, Adaptive Force, and Health Scaling for your rune shards. Start with Rod of Ages as your first item, then Archangel's Staff as the second item. Finish your build with Rylai's Crystal Scepter, Liandry's Torment, and Rabadon's Deathcap. Max E first, followed by Q, and then W for your ability order.

Situational Cassiopeia Runes and Items

Depending on your game's context, matchup, and enemy champions, it may be necessary to adjust your itemization or select specific runes. Carefully consider the team compositions, game state, and enemy champions to adjust your build accordingly. For rune shards, you might want to take Armor or Magic Resist based on your opponent's primary damage type.